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KMID : 1038620140320040262
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Radiation Oncology Journal
2014 Volume.32 No. 4 p.262 ~ p.265
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Radiation recall dermatitis induced by tamoxifen during adjuvant breast cancer treatment
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Rhee Ji-Young
Kim Gwi-Eon
Lee Chang-Hyun
Kwon Jung-Mi
Han Sang-Hoon
Kim Young-Suk
Kim Woo-Kun
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Abstract
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Tamoxifen and radiotherapy are used in breast cancer treatment worldwide. Radiation recall dermatitis (RRD), induced by tamoxifen, has been rarely reported. Herein, we report a RRD case induced by tamoxifen. A 47-year-old woman had a right quadrantectomy and an axillary lymph node dissection due to breast cancer. The tumor was staged pT2N0; it was hormone receptor positive, and human epidermal growth factor receptor 2 negative. The patient received adjuvant chemotherapy followed by tamoxifen and radiotherapy. After 22 months of tamoxifen, the patient developed a localized heating sensation, tenderness, edema, and redness at the irradiated area of the right breast. The symptoms improved within 1 week without treatment. Three weeks later, however, the patient developed similar symptoms in the same area of the breast. She continued tamoxifen before and during dermatitis, and symptoms resolved within 1 week.
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KEYWORD
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Tamoxifen, Radiation recall dermatitis, Treatment
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